I was thinking about what an updated CS80 would be like. Maybe it goes without saying, but I would want it to be lighter, smaller, more reliable, updated with modern connectivity, and much more affordable - Maybe $2500-$3000 depending on keybed type / size.
As a UI designer, one of the trickiest things about updating a beloved all-analog design is how to balance making it approachable and intuitive for new musicians, keeping the hardware costs reasonable re: control design, and still maintaining the CS80's signature expressivity.
And even then, I would ask, what controls are innate to its "CS80-ness" and what could be replaced or updated? What controls really need to be on the front panel?
For instance, if we were to try to go to digital controls/displays and keep a 1:1 recreation of the original, we start going down the road of the Alesis Andromeda or the John Bowen Solaris, or the recently announced Modulus 002; then we're making a boutique synth priced out of the range of gigging musicians.
From a manufacturing perspective I'd want to reduce parts, make things more (small-m) modular for the sake of testing and servicing; get rid of the cable spaghetti; and lower the power use overall.
How do you balance this with keeping the CS80 sound? Does a filter really need all-discrete components, or will surface-mount do? Or could you reduce that all to custom analog IC? I don't have an easy answer for that, but I think a company with patents and resources could solve it if they set their minds to it.
If we're not going to be purist about it... I wouldn't be opposed to a virtual analog or hybrid version if it could get 95% of the way there. Leaving aside the CS80V, recent synths like the Elektron Analog Keys, Studiologic Sledge and the Roland GAIA show that you can get a big sound at a reasonable price, and still have good live-performance / quick-edit responsiveness.
Looking at the GAIA specifically, I think it balances the knobbiness vs "mode buttons" question very well. Would you really need two sets of physical controls for each voice if you had something like the GAIA's 3 voices?
Yamaha seem more focused on the "performance keyboards" segment of the market these days. They've steadily but surely moved away from "knobbiness" - whereas Korg and Roland have enthusiastically picked up the torch.
I don't know if it's in the cards, but imagine a team-up where Roland were to produce a VA CS-8000 under license from Yamaha... one that could be battery-powered and easily carried under one arm?

Imagine some of the better Roland design choices and proprietary features like the D-beam alongside the ribbon controller and modulation levers... or replacing levers for digital ribbons, etc.